Propanoate metabolism depicts the metabolism of propionic acid. Propionic acid basically stems from the production of the acid by either gut or skin microflora. Propanoate is converted into propanol adenylate via propionyl-CoA synthetase and acetyl-CoA synthetase in mitochondrial. The propionyl adenylate then is converted into propionyl coenzyme A (propionyl-CoA), which is carboxylated into D-methylmalonyl-CoA via propionyl-CoA carboxylase. The resulting compound is isomerized into L-methylmalonyl-CoA via methylmalonyl-CoA epimerase. L-methylmalonyl-CoA can enter into citric acid cycle by converting into succinyl-CoA via methylmalonyl CoA mutase. cyclohexyl butanoate https://metabolomics.creative-proteomics.com/propanoate-metabolism-service.htm
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